Nelson Higher Education

Higher Education

Experimental Organic Chemistry: A Miniscale & Microscale Approach, 6th Edition

  • John C. Gilbert
  • Stephen F. Martin
  • ISBN-10: 1305080467
  • ISBN-13: 9781305080461
  • 960 Pages | Hardcover
  • Previous Editions: 2011, 2006, 2002
  • COPYRIGHT: 2016 Published
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Overview

About the Product

Providing even more emphasis on inquiry-based learning and student collaboration and featuring three new green experiments and more than a dozen newly developed experiments, this Sixth Edition of Gilbert and Martin's proven EXPERIMENTAL ORGANIC CHEMISTRY contains procedures for both miniscale (also known as small scale) and microscale users. The book offers an early focus on equipment, record keeping, and safety in the laboratory, and then guides students step by step through the theoretical and mechanistic principles underlying the experiments and the laboratory techniques needed to perform them with confidence. Students learn how to use a range of experimental techniques to synthesize compounds and analyze their properties, complete multi-step syntheses of organic compounds, and solve structures of unknown compounds. New experiments in Chapter 17 and 18 demonstrate the potential of chiral agents in fostering enantioselectivity and of performing solvent-free reactions. The bioorganic experiment in Chapter 24 reflects the increasing emphasis on bioorganic chemistry in the course and gives students an opportunity to accomplish a mechanistically interesting and synthetically important coupling of two -amino acids to produce a dipeptide.

Features

  • Safety is emphasized through "Safety Alerts" and "Wrapping It Up" sections that highlight possible hazards and proper disposal of spent chemicals.

  • Fascinating "Historical Highlights" familiarize students with the lives of chemical pioneers who have advanced the field of chemistry.

  • Accurately drawn art shows students how to set up an experiment with confidence.

  • Margin drawings of equipment remind students about the set up for such techniques as distillation and reflux.

  • Each experiment begins with a thorough discussion of the theory and procedures involved and lays out experimental procedures in a clear format to enhance student understanding.

  • Featuring chemist-developed content, OWLv2 with LabSkills is the only system designed to elevate thinking through Mastery Learning. Developed to prepare students for their lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. With detailed, instant feedback and interactive learning resources, students get the help they need when they need it.

About the Author

John C. Gilbert

Jack Gilbert joined the faculty of the University of Texas at Austin in 1965 and moved to Santa Clara University in 2007, where he is Professor of Chemistry & Biochemistry. He received the Advisory Council Teaching Excellence Award at UT the 2002–2003 academic year, as well as many other recognitions in teaching. While at UT, he co-authored several editions of the first laboratory textbook in organic chemistry that emphasized reactions mechanisms, as well as laboratory techniques, including spectroscopy. He continues to update the textbook, now with the able assistance of Steve Martin.

Stephen F. Martin

Stephen Martin received his B. S. degree in chemistry from the University of New Mexico in 1968 and his Ph.D. degree from Princeton University in 1972. After postdoctoral years at the University of Munich and MIT, he joined the faculty at The University of Texas at Austin in 1974, where he currently holds the M. June and J. Virgil Waggoner Regents Chair in Chemistry. His research interests lie broadly in organic and bioorganic chemistry. In the former area, his endeavors involve developing and applying new methods and strategies to the syntheses of biologically active natural and non-natural products, especially those containing nitrogen and oxygen heterocyclic subunits. In the biological arena, he is studying fundamental aspects of molecular recognition in biological systems with a particular focus on how making specific structural changes in a ligand, particularly with respect to preorganization and nonpolar surface area, affect energetics and dynamics in protein-ligand interactions. He has received a number of awards including a NIH Career Development Award, an American Cyanamid Academic Award, an Alexander von Humboldt Award, an Arthur C. Cope Scholar Award, a Japanese Society for the Promotion of Science Award, a Wyeth Research Award, and the International Society of Heterocyclic Chemistry Senior Award. He is a fellow of the American Association for the Advancement of Science and has served as a consultant for a number of pharmaceutical and biotechnology companies. He is the regional editor of “Tetrahedron for the Americas.” He has delivered numerous invited lectures at national and international meetings, academic institutions, and industrial companies, and has published over 300 scientific papers in primary journals together with several reviews and articles in books. He is also co-author of “Experimental Organic Chemistry: A Miniscale and Microscale Approach.”

Table of Contents

1. Introduction, Record Keeping, and Laboratory Safety.
2. Techniques and Apparatus.
3. Solids: Recrystallization and Melting Points.
4. Liquids: Distillation and Boiling Points.
5. Extraction.
6. Chromatography.
7. Stereoisomers.
8. Spectral Methods.
9. Alkanes.
10. Alkenes.
11. Alkynes.
12. Dienes: The Diels-Alder Reaction.
13. Kinetic and Thermodynamic Control of a Reaction.
14. Nucleophilic Aliphatic Substitution: Preparation of Alkyl Halides.
15. Electrophilic Aromatic Substitution.
16. Oxidation of Alcohols and Carbonyl Compounds.
17. Reduction Reactions of Double Bonds: Alkenes, Carbonyl Compounds, and lmines.
18. Reactions of Carbonyl Compounds.
19. Organometallic Chemistry.
20. Carboxylic Acids and Their Derivatives.
21. Multistep Organic Synthesis.
22. Polymers.
23. Carbohydrates.
24. Amino Acids and Peptides.
25. Identifying Organic Compounds (ONLINE ONLY).
26. The Literature of Organic Chemistry (ONLINE ONLY).

New to this edition

  • With three new green experiments and over a dozen newly developed experiments (in chapters 3, 10, and 14-20) this edition is considerably enhanced to provide a comprehensive lab experience for students.
  • To make room for new experiments, Chapters 25 (Identifying Organic Compounds) and 26 (The Literature of Organic Chemistry) have been moved online.
  • All images have been checked, with many revised and updated as needed.
  • New spectra have been added and are available online.
  • OWLv2 with LabSkills and MindTap Reader: Featuring chemist-developed content, OWLv2 with LabSkills is the only system designed to elevate thinking through Mastery Learning. Developed to prepare students for their lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. With detailed, instant feedback and interactive learning resources, students get the help they need when they need it.

Supplements

All supplements have been updated in coordination with the Main title.
Please see Main title page for new to this edition information.

Instructor Supplements

Website  (ISBN-10: 1305581008 | ISBN-13: 9781305581005)

This Instructor Resource Site, accessible from the Instructor Resource Center when you sign in at login.cengage.com, provides access to the Instructor’s Manual, Complete Pre-Lab Exercises, and MSDS.

OWLv2 with LabSkills 6-Months Instant Access  (ISBN-10: 1305387694 | ISBN-13: 9781305387690)

Students can use this ISBN at www.CENGAGEbrain.com to purchase instant access to OWLv2, the most trusted online learning solution for chemistry. Featuring chemist-developed content, OWLv2 with LabSkills is the only system designed to elevate thinking through Mastery Learning. Developed to prepare students for their lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. With detailed, instant feedback and interactive learning resources, students get the help they need when they need it. Visit www.CENGAGE.com/owlv2 to learn more.

OWLv2 with LabSkills, 4 terms (24 months) Instant Access  (ISBN-10: 1305387678 | ISBN-13: 9781305387676)

Students can use this ISBN at www.CENGAGEbrain.com to purchase instant access to OWLv2, the most trusted online learning solution for chemistry. Featuring chemist-developed content, OWLv2 with LabSkills is the only system designed to elevate thinking through Mastery Learning. Developed to prepare students for their lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. With detailed, instant feedback and interactive learning resources, students get the help they need when they need it. Visit www.CENGAGE.com/owlv2 to learn more.

Student Supplements

OWLv2 with LabSkills 6-Months Instant Access  (ISBN-10: 1305387694 | ISBN-13: 9781305387690)

If your instructor requires OWLv2 for this course, you can use this ISBN to purchase instant access at www.CENGAGEbrain.com. OWLv2 with LabSkills is the most powerful online learning solution for chemistry, and now brings personalized study tools to your lab course! Designed to prepare you for lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. All assignments include detailed, instant feedback and interactive learning resources. To learn more, visit www.CENGAGE.com/owlv2 or talk to your instructor.

OWLv2 with LabSkills, 4 terms (24 months) Instant Access  (ISBN-10: 1305387678 | ISBN-13: 9781305387676)

If your instructor requires OWLv2 for this course, you can use this ISBN to purchase instant access at www.CENGAGEbrain.com. OWLv2 with LabSkills is the most powerful online learning solution for chemistry, and now brings personalized study tools to your lab course! Designed to prepare you for lab sessions through pre-lab assignments, this new OWLv2 course includes LabSkills pre-lab techniques, a MindTap Reader of the lab manual, and pre and post-lab content specific to the experiments. All assignments include detailed, instant feedback and interactive learning resources. To learn more, visit www.CENGAGE.com/owlv2 or talk to your instructor.