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Web LinksUNIT 30AUNIT 30BUNIT 30C
UNIT 30D
Chapter 18 Endocrine SystemPage 69 Mini-Investigation: Chemical Signals and Sports Find out more about the use of banned drugs in sports. (a) Choose one banned drug and explain the unfair advantage it provides. (b) What are some of the health risks associated with its use? (c) Identify some of the technologies used to detect whether an athlete is using the drug. Anabolic
Steroids Olympic
Medical Commission Doping Common
Drugs of Use and Abuse Page 81 Web Activity - Canadian Achievers: Banting and Best Frederick Banting (1891-1941) served in World War I as a doctor. On returning from the war, he became interested in diabetes research. At the time, diabetes was thought to be caused by a deficiency of a hormone located in specialized cells of the pancreas. However, extracting the hormone from the pancreas presented a problem since the pancreas also stores digestion enzymes capable of breaking down the protein hormone. In 1921, Banting approached John J.R. MacLeod, a professor at the University of Toronto , with his idea for isolating the hormone. MacLeod assigned Banting a makeshift laboratory as well as an assistant, Charles Best, who was a graduate student in biochemistry. Working together, Banting and Best (Figure 3) were able to isolate insulin and to then use the hormone as the first successful treatment of diabetes. Follow the links on the Nelson Web site to learn more about the remarkable work of these two scientists. You might use these questions to guide your research: . How were they able to obtain pancreas tissue in which only cells from the islets of Langerhans were living? . Why was this important to their success? . In 1923, Banting and MacLeod were awarded the Nobel Prize for physiology and medicine. Best was not included in the award. Why? What is your opinion on this event? Banting and Best) tied the pancreatic duct of dogs, and waited seven weeks for the pancreas to shrivel.Although the cells producing digestive enzymes deteriorated, cells from the islets of Langerhans remained. The hormone was then extracted from the pancreas. When the hormone was injected into dogs that had had their pancreases removed, symptoms of diabetes ceased. Banting and Best wanted to call the hormone isletin , but MacLeod insisted that it be called insulin . When Banting and MacLeod were awarded the Nobel Prize for physiology and medicine in 1923, Banting was furious that Charles Best, his coworker, had not been included. MacLeod, the professor who had contributed laboratory space, had gotten the glory instead. CBC
Archives -- Banting and Best Banting
and Best Isolate Insulin
Page 81 Career Connection: Entrepreneur In addition to insulin injections, diabetics maintain their blood sugar levels by regulating their diets. Food choices are very important for diabetics. The Nelson Web site has information on recipes suitable for diabetics. List possible opportunities for an entrepreneur in the area of cuisine for diabetics. What information would you need to collect for a business plan? Diabetic Gourmet Favourite
Recipes Diabetes Help Center
Business
Start-up Assistant
Page 93 Web Activity: Homeostasis and Space Travel As humans spend more time in space, scientists have found that the microgravity environment changes the ability of the body to maintain homeostasis. Astronauts who spend substantial periods in space are at most higher risk of developing hypercationa, a condition that causes kidney stone formation. Aldosterone and ADH work together to adjust urine volume and reabsorption of salts by the kidney. In this activity, you will infer the role of ADH and aldosterone from data on blood and urine composition, and relate it to the changes in homeostasis during space flight. Follow this link to the Web Activity Additional information on homeostasis in the human body and microgravity environments can be found at these links: International Space Station Physiology
Page 95 Section 18.4 Questions 11. The International Olympic Committee has banned performance-enhancing drugs. Research the classes of banned drugs. Describe the advantages and side effects of one drug in each class. Drugs
in Sports Drug
Use in Sports Canadian
Centre for Ethics in Sport The
2005 Prohibited List
Page 101 Chapter 18 Review 26. The incidence of diabetes in North America has risen dramatically in the last few decades. Research how changes in diet have affected the incidence of diabetes in the Aboriginal population. Aboriginal
Diabetes and Diet Diabetes:
An Aboriginal Health Crisis
Page 103 Unit 30 A Performance Task: Determining the Effects of Caffeine on Homeostasis (i) Compare your results with available standards, either determined by your group or from another source, such as the Internet. Describe the comparison. The
Effects of Caffeine on Plants Caffeine
Caffeine
and Homeostasis Effects
of Caffeine on Ca2+ Homeostatsis Caffeine and Hypertension
in Women
Page 107 Unit 30 A Review 27. In June 2000, a team of researchers at the Massachusetts Institute of Technology and Bell Labs reported that they had created an electronic circuit based on the cerebral cortex, the brain's centre of intelligence. Lauded as the first artificial circuit to mimic brain activity, it was modelled on the much larger network of natural neurons and feedback loops in the human brain. Use several sources to research artificial intelligence or neuromorphic engineering, and find out how this circuitry works. Search for information in newspapers, periodicals, CD-ROMs, and on the Internet. Artificial Intelligence Electronic
Circuit that Mimics the Brain When
will computer hardware match the human brain? Electronic
Circuit Replicates Brain Activity Artificial
Brains
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